WHY WORK WITH US
Harness The Power of Metabolic Science
We developed the first ketone-powered skincare active and booster, Ketones for Complexes™. K4C™ activates deep cellular processes that nurture long-lasting resilience in the skin and increase the uptake and efficacy of paired cosmetic compounds.
Work with us to create outstanding products that promote both beauty and health for your customers, combining regenerative and preventative care.
Pioneering Metabolic Skincare, Powered by Space Science
KETOCOSMESI was founded to bring the frontiers of space research into everyday skincare. In partnership with JAXA and leading genome scientists, we’ve developed patented bioactivated molecules that reprogram skin epigenetics via ultrasonic nebulization—ushering in a new era of metabolic skincare innovation.
Targeting Deep Cellular Processes
Most skincare ingredients struggle to penetrate beyond the surface, but K4C™ is engineered for deep absorption.
Unlike conventional actives that remain trapped in the stratum corneum, K4C™ reaches the living epidermal cells, where aging and cellular stress take hold.
Independent percutaneous penetration tests confirm its ability to reach deep into the epidermis, delivering targeted support exactly where skin needs it most. Wrinkle-repair potential by measuring the rate of cell migration and closure of the scratch over time. K4C achieved a 52% closure of the scratch in vitro, confirming skin regeneration and wrinkle repair by inducing the natural healing process.
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Activating Epidermal Metabolism
K4C supports the metabolic and bioenergetic effects of a skin treatment K4C, suggesting a potential role in skin regeneration and energy support. Left Figure: The shift in metabolite profile from glycolytic intermediates to ketone-derived products (AcAc, Acetyl-CoA) suggests K4C treatment enhances mitochondrial oxidative metabolism, which is associated with improved cellular energy status—a key factor in skin repair and anti-aging processes.
Bottom Figure: Enhanced ATP production supports increased cellular activity, including collagen synthesis, cell migration, and tissue repair mechanisms—processes essential for skin regeneration and wrinkle reduction.
Boosting the Uptake
& Efficacy of
Co-ingredients
K4C™ amplifies the efficacy of co-ingredients in two ways.
Optimizing the skin environment – By reducing oxidative stress, inflammation, and dehydration in the epidermis, K4C™ creates the ideal conditions for active ingredients to work more effectively.
Enhancing ingredient delivery – Acting as a carrier for compatible cosmetic actives, K4C™ facilitates deeper absorption while fueling skin cells with the energy needed to process and utilize these ingredients.
